Select this product for Molecular Innovations name, Mouse Prothrombin and product number, MFII.Mouse Factor II (Prothrombin) Purified from Innovative Research has been purified from US origin mouse plasma. This is a frozen liquid buffered in 100 mM Tris-HCl/0.15 M NaCl/pH 7.4, and a purity of greater than 95% as determined by SDS-PAGE analysis (showing no reduction when incubated with 2-mercaptoethanol).Prothrombin (Coagulation Factor II) is converted to active Thrombin (FIIa) during the coagulation cascade. This happens when Factor Xa and its cofactor, Factor V, together cleave Prothrombin in two, creating a fragment (fragment 1.2, which is formed from the N-terminal Gla domain and two Kringle domains of Prothrombin) and thrombin (containing only the serine protease domain).More Details: Source: Mouse Plasma Purification: Chromatographically purified Purity: >95% by SDS-PAGE Storage Conditions: -60 to -80C For research use only. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.